Module  5.4:  Developmental Aspects of Skeletal System 

As we age, our bones are as dynamics as any other body system - constantly remodeling and growing. In this module we will learn the process of bone formation as well as the body's lifelong duty to maintain healthy bones.   

Module 5.4 Warm-Up 

- Directions: For this module warm-up you will be examining the feedback process in bone formation and upkeep. 

- In your module guide....

Sketch a balance (see below) that show the feedback mechanisms in maintaining calcium homeostasis of blood. (See textbook for details).

page 310 in YOUR text and 

page 187 in class text 

Essential Vocab: 

osteoblasts, osteoclasts, osteogenic cells, nutrient foramina, endosteum, dipole, red marrow, red marrow cavities, osteoblasts, haversian system, osteon, lamella, lamellar bone, central canal, perforating canals, osteocytes, lacunae, interstitial lamellae, osteoid, ossification, osteogenesis, membrane bone, cartilage, endochondrial bone, endochondrial ossification, primary ossification center, secondary ossification centers, bone remodeling, bone deposit, bone reabsorption, parathyroid hormone, calcitonin

Module Objectives: 

4. Bone Development

(Initial Development)

4.1 – Describe the process of bone formation in the fetus and summarize the events of remodeling throughout life

(Remodeling and Repair)

4.2 – Describe the steps of fracture repair

4.3 – Explain how physical stress and stress hormones regulate bone remodeling

4.4 – Compare the locations and remodeling functions of the osteoblasts, osteocytes, and osteoclasts